Sam DePalma

PhD Candidate
Biomedical Engineering, University of Michigan

samdep (at) umich (dot) edu


Hometown: Southbury, Connecticut

Education: BS in Biomedical Engineering, Boston University, 2018

Research interests: My previous research has focused on synthesizing novel biomaterials for applications in drug delivery and biosensing. Expanding upon these experiences, I am currently interested in developing fibrous synthetic biomaterial systems to study how extracellular matrix properties influence tissue development and functionality. By controlling matrix mechanics, I aim to examine how cardiomyocytes interact with their environment to create complex functioning cardiac tissues. Overall, this research will help to guide efforts within regenerative medicine to repair damaged and diseased heart muscle.

Outside of lab interests: Outside the lab, you can usually find me running around Ann Arbor training for my next marathon. I also enjoy trying new restaurants, going to local bars/breweries with friends, and watching sports – including Michigan football.


Davidson CD, Jayco DKP, Matera DL, DePalma SJ, Hiraki HL, Wang WY, Baker BM. "Myofibroblast activation in synthetic fibrous matrices composed of dextran vinyl sulfone," Acta Biomaterialia, 2020, doi:10.1013/j.actbio.2020.01.009.